If so, using a caffeine shampoo could be just what you need. According to a study published in the International Journal of Dermatology, caffeine was proven capable of reversing the inhibitory effects testosterone has on the hair follicles. This study aimed to determine the effects of caffeine and testosterone on the growth of human hair follicles in vitro. This was made possible by collecting ex vivo hair follicles taken from scalp biopsies of men suffering from androgenetic alopecia (AGA) and testing them in vitro to establish the maximal inhibitory concentration of testosterone as well as the caffeine concentration necessary to reverse such effect. A meaningful suppression in follicle growth was seen in hair follicles treated with 5ug/ml of testosterone. Caffeine neutralized this suppression in concentrations of 0.001% and 0.005%. When used alone, caffeine significantly stimulated hair follicle growth. Because dihydrotestosterone (DHT) is the agent responsible for causing AGA, and DHT is a result of testosterone conversion, inhibiting testosterone could lead to inhibition of AGA. The results produced in vitro by this study set the basis for the clinical efficacy of topically applied caffeine for treatment of AGA, thus the creation of caffeine shampoos.
A few of the caffeine shampoos currently available include Alpecin caffeine shampoo, Organix Awakening Shampoo, Alaffia Shea and Revitalizing Shampoo (infused with Robusta coffee), and Dr. Wolff Plantur 39 Caffeine Shampoo. The quantity of caffeine in the Alpecin shampoo is equivalent to about 1/5 cup of coffee. Several of these products use coffee beans as the source of caffeine. It’s possible that liquid caffeine could be added to your usual shampoo for a similar invigorating effect. Caffeine shampoos should be allowed to sit on the scalp about 2 minutes to ensure proper absorption. Presently, Dr. Cole is working towards patenting his very own line of caffeine shampoo.