Hair Transplant Blog Featuring John P. Cole, MD

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Women Hair Loss Can PRP and Acell grow hair?

I am female and have a lot fallen hair during 5 mounts last 2 years I had same problem but I had mesotrophy my hair and it was effective for me. I would like to know prp is working for growing the new hair or not because my husband done prp 8 mount ago but nothing is change and he didn’t get back any result from it please consulting me.

PRP and Acell can improve hair diameter and coverage in up to 70% of individuals who are suffering from miniaturizing hair loss. PRP and Acell also seem to work in some patients with alopecia areata. PRP and Acell do improve hair quality in all individuals. PRP must be activated so that the platelets release their growth factors, however. Some physicians inject the PRP, but never activate the platelets. Platelet activation is an important aspect of of the PRP treatment. Without platelet activation, you should not expect any benefit from the PRP. Of course with platelet activation, the PRP seems to improve coverage in only 70% of the patients who receive the treatment.

glaucoma Glaucoma Treatment Can Grow Human Hair?

Glaucoma drug treat hair loss

According to materials provided by the Federation of American Societies for Experimental Biology, The drug bimatoprost that is used to treat glaucoma actually grows human hair.

It’s been commercially available and even promoted as a way to lengthen eyelashes, but recent studies show that it can actually grow human hair from the scalp.

“We hope this study will lead to the development of a new therapy for balding which should improve the quality of life for many people with hair loss,” said Valerie Randall, a researcher involved in the work from the University of Bradford, Bradford, UK. “Further research should increase our understanding of how hair follicles work and thereby allow new therapeutic approaches for many hair growth disorders.”

Related to this new study, Randall and colleagues conducted three sets of experiments. Two involved human cells and the other involved mice. The tests on human cells involved using hair follicles growing in organ culture as well as those taken directly from the human scalp. In both of these experiments, the scientists found that bimatoprost actually led to hair growth. The third set of experiments involved applying bimatoprost to bald spots on mice. As was the case with human cells, the drug caused the hair to regrow.

“Given that the drug is already approved for human use and its safety profile is generally understood, this looks like a promising discovery that has been right in front of our eyes the whole time.”

This is a 3 months post-op results from a medical management that includes Platelet Rich Plasma (PRP), Acell, and thrombin. The patient is 32 years old with an unusual Norwood 3V pattern of hair loss. The patient had thinning in the frontal hairline, mid-scalp(top) and crown.
The patient had a successful FUE (CIT) hair transplant procedure, We placed 1992 grafts to the hairline and top.
In most cases grafting into the crown normally requires more donor hair to cover the crown than any other recipient area on the scalp.
We decided to start treatment in this crown with Platelet Rich Plasma (PRP), Acell, and thrombin therapy. The patient had a great response to medical management alone.
As you can see from the photo, At 3 month follow-up we noticed that he had more coverage in the crown where we used the PRP, Acell, and thrombin therapy.

(Click On the image to view full size)
PRP THROMBIN TREATMENT 300x200 4 Months Results with Platelet Rich Plasma (PRP), Acell, and thrombin


I find this interesting.  This is another FUE extraction site treated with ACEll in a hyaluronic acid mixture after 5 weeks.  It is still too early to tell if the hair might regrow in the extraction site though I have seen this.  It does appear that a single hair is forming in the extraction site, which appear as a black nub.  What is interesting is the appearance of a capillary in the skin.  These are usually missing following FUE and help lead to the loss of pigment in the extraction site.  I’ve done enough FUE to spot extraction sites anytime I look at a donor area even when no hypopigmentation occurs.  It is an observation based on experience with FUE.  With this donor area, I could not find any evidence that FUE was performed.  The red circle is where I would expect a follicular unit to be.  The entire donor area looked like this.  The black circle is 10 sq mm.  I had the dermlite people make this reticule for me.

The long hair after 5 weeks is a result of a completely non-shaven procedure of 1464 grafts.  I call this C2G.  It is still to early to say for sure because I need more results, but this is an example of what I have seen in donor areas treated fully with ACELL with my method of FUE where I use minimal depth control.  The initial problem was treating all the extraction sites with a powder.  I overcame this with mixing it in a viscous hyaluronic acid.  More recently I have been mixing in a more viscous cellulose.  I have a few comparative examples where I am looking at powder, hyaluronic acid, and cellulose.  Time will hopefully tell. I think the minimal depth incision technique along with Acell may result in better healing than a full depth incision.  Maybe we will see more hair regrowth over time.   Maybe not.  Still no one could comb through this donor area and find any evidence that a hair transplant had been done.  It appears that we really are coming full circle today.  Not only have we produced optimal results in the recipient area such that you cannot tell that a hair transplant has been done.  Even the trained eye cannot see evidence that a hair transplant was done in the recipient area.

Slide11 Healing with CIT FUE Hair Transplant and Acell